Epic Powder delivers precision micronization solutions for pharmaceutical manufacturers worldwide. When a leading API producer in Guangdong needed to micronize Nifedipine (a key hypertension drug) they turned to our proven disc jet mill technology for the API grinding solution.
Nifedipine demands extremely fine particles. Finer particles mean faster dissolution and better bioavailability. Traditional mills often create wide particle size distribution, low yield, or heat damage. Our client required consistent sub-3-micron results at commercial-scale throughput.
The solution was clear: Destansı Toz MQP30 Disc Jet Mill. This spiral disc jet mill uses high-speed compressed gas to create powerful particle-on-particle collisions. Minimal heat, zero metal contamination, and ultra-narrow particle size distribution makes it perfect for heat-sensitive APIs like Nifedipine.
The MQP30 integrates easily into GMP production lines. Quick disassembly and CIP (Clean-In-Place) design ensure fast batch changeovers. Operators control particle size precisely by adjusting feed rate and grinding pressure.
After installation and optimization, the results spoke for themselves. The client achieved stable, repeatable micronization with excellent yield for Nifedipine API grinding. Downstream formulation became smoother. Dissolution rates improved significantly. Regulatory documentation was straightforward thanks to consistent quality. Ready to micronize your API with precision? Contact Destansı Toz today for Nifedipine or any other active pharmaceutical ingredient.
Technical Parameters:
API: Nifedipine
Particle Size: d90 = 2.4 µm
Output: 32 kg/h
